Antibody Pairs

Overview

BOT Bioscience’s Antibody Pairs Series is a specialized reagent set designed for sandwich immunoassays (e.g., ELISA, lateral flow assay), consisting of matched capture antibodies and detection antibodies. It enables specific capture and signal detection of target analytes (proteins, cytokines, antigens), supporting applications in disease diagnosis, biomarker detection, and biological sample quantification.

 

The series covers diverse target types, including cytokines (IL-2, IL-6, IFN-γ), tumor markers (CA125, PSA, CEA), infectious disease antigens (COVID-19 S protein, influenza HA protein), and common proteins (β-actin, IgG). Each pair undergoes strict matching validation to ensure high binding affinity, low cross-reactivity, and consistent assay performance, adapting to various sample matrices (serum, plasma, cell culture supernatant) and detection platforms.

 

Categories and Applications

Antibody Pair Category (by Target Type)

Key Target Examples

Common Application Scenarios

Cytokine Antibody Pairs

IL-2, IL-6, IFN-γ, TNF-α, IL-17A

1. Immunology research: Quantification of cytokine levels in inflammatory or immune response models;
2. Clinical monitoring: Detection of serum cytokines in autoimmune diseases (e.g., rheumatoid arthritis) or infections;
3. Drug development: Evaluation of immunomodulatory drug efficacy by measuring cytokine secretion

Tumor Marker Antibody Pairs

CA125, PSA, CEA, AFP, HER2

1. Cancer diagnosis: Preliminary screening of tumor markers in serum (e.g., PSA for prostate cancer);
2. Prognosis monitoring: Tracking changes in tumor marker levels during cancer treatment (e.g., CEA for colorectal cancer);
3. Early detection: Low-abundance tumor marker quantification in high-risk populations

Infectious Disease Antigen Antibody Pairs

COVID-19 S/RBD protein, Influenza HA protein, Hepatitis B surface antigen (HBsAg)

1. Pathogen detection: Rapid diagnosis of infectious diseases via ELISA or lateral flow assays (e.g., COVID-19 antigen testing);
2. Epidemiological survey: Large-scale screening of pathogen antigens in populations;
3. Vaccine evaluation: Detection of antigen levels in vaccine preparations or post-vaccination samples

Common Protein Antibody Pairs

β-actin, GAPDH, IgG, Albumin

1. Internal reference validation: Quantification of housekeeping proteins (β-actin, GAPDH) in Western blot or ELISA;
2. Protein purification quality control: Detection of target protein purity in recombinant protein preparations;
3. Clinical biochemistry: Measurement of serum albumin or IgG levels in liver/kidney disease patients

 

To learn more about our products, please search through keywords or contact us via email at info@bot-bioscience.com. We are looking forward to assisting you in finding the most suitable antibody pairs for your research.

 

Products Highlights

Strictly matched capture/detection antibodies, ensuring high assay specificity and sensitivity

Covers cytokines, tumor markers, pathogens, and common proteins for diverse applications

Validated for multiple sample types (serum, plasma, cell culture supernatant) and platforms

Stable batch-to-batch performance with detailed QC reports (detection limit, CV value)

Ready-to-use formats available, reducing experimental setup time

Custom antibody pair development service for unique target analytes

Cost-effective options for small-volume trials and large-scale production